In a medium microwave-safe bowl, combine white chocolate chips, sweetened condensed milk and butter. Microwave on high for 30 seconds. Stir ingredients together and microwave for an additional 30 seconds; stir until melted and smooth. Stir in orange extract, cranberries, and pistachios until evenly combined.

Using a small cookie scoop, roll the mixture into 1-inch balls. (The mixture will be sticky) Refrigerate for 30 minutes.

Re-roll the balls and refrigerate for an additional 30 minutes.

Sift confectioners’ sugar into a bowl. Roll each truffle into the confectioners’ sugar to coat them well.

Store leftover truffles in an airtight container in the refrigerator for up to 1 week or freeze for longer storage.